Description
Composition
Each Tablet Contains: Methenolone Acetate 25 mg
INDICATIONS
Primobolic is used mainly in the treatment of anemia due to bone marrow failure.
CONTRA-INDICATIONS
Not intended for use in children. Known or suspected prostatic carcinoma and mammary carcinoma in the male. Not intended for use in female patients other than those with disseminated breast cancer. Contraindicated in nephrosis or the nephrotic phase of nephritis, cardiac and renal failure, hypercalcaemia, oedema, jaundice, liver disease with impaired bilirubin excretion, testicular and hepatic carcinoma.
DOSAGE AND DIRECTIONS FOR USE
The usual initial adult dosage is 25mg daily.
SIDE-EFFECTS AND SPECIALPRECAUTIONS
Virilisation which appears in sensitive women as hoarseness, acne, hirsutism, and increased libido; in prepubertal boys as an increased frequency of erections and phallic enlargement, and in girls as an increase of pubic hair and clitoral hypertrophy. Hoarseness may be the first symptom of vocal change which may end in a long-lasting, sometimes irreversible deepening of the voice.
OTHER ADVERSE REACTIONS MAYINCLUDE
Oligospermia and decreased ejaculatory volume; Suppression of ovarian activity, atrophy of the breasts and endometrial tissue. Amenorrhoea and inhibition of spermatogenesis. Water and salt retention. Premature epiphyseal closure. If signs of virilisation develop, treatment should be discontinued. Increase in nitrogen retention and skeletal weight; Oedema; Increased vascularity of the skin; Increased growth of the bone; Elderly males may become over-stimulated.
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